Demis Hassabis and John Jumper Receive Nobel Prize for Chemistry

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This morning, Co-founder and CEO of Google DeepMind and Isomorphic Labs Sir Demis Hassabis, and Google DeepMind Director Dr. John Jumper were co-awarded the 2024 Nobel Prize in Chemistry for their work developing AlphaFold, a groundbreaking AI system that predicts the 3D structure of proteins from their amino acid sequences. David Baker was also co-awarded for his work on computational protein design.

Before AlphaFold, predicting the structure of a protein was a complex and time-consuming process. AlphaFold’s predictions, made freely available through the AlphaFold Protein Structure Database, have provided over 2 million scientists and researchers from 190 countries with a powerful tool for making new discoveries. The AlphaFold 2 paper, published in 2021, remains one of the most-cited publications of all time.

AlphaFold’s contributions to science have received widespread recognition, including the 2023 Albert Lasker Basic Medical Research Award, the 2023 Breakthrough Prize in Life Sciences, the 2023 Canada Gairdner International Award, the 2024 Clarivate Citation Laureate award, and the 2024 Keio Medical Science Prize Award.

Artificial intelligence (AI) has demonstrated significant potential for use in scientific research, and AlphaFold serves as a proof-of-concept. As more scientists embrace AI for various applications—including data building, experiment simulation, drug design, and modeling complexity—we anticipate continued foundational breakthroughs in scientific knowledge.

Following the announcement, Demis Hassabis stated: 
"Receiving the Nobel Prize is the honour of a lifetime. Thank you to the Royal Swedish Academy of Sciences, to John Jumper and the AlphaFold team, the wider DeepMind and Google teams, and to all my colleagues past and present who made this moment possible. I’ve dedicated my career to advancing AI because of its unparalleled potential to improve the lives of billions of people. AlphaFold has already been used by more than two million researchers to advance critical work, from enzyme design to drug discovery. I hope we'll look back on AlphaFold as the first proof point of AI's incredible potential to accelerate scientific discovery."

In response to the Nobel Prize news, John Jumper commented: 
"Thank you to the Royal Swedish Academy of Sciences for this extraordinary honor. We are truly honored to be recognized for delivering on the long promise of computational biology to help us understand the protein world and to support the incredible work of experimental biologists. This serves as a key demonstration that AI will hasten scientific progress and ultimately aid in understanding disease and developing therapeutics. This achievement reflects the efforts of an exceptional team at Google DeepMind and recognizes their remarkable contributions.

Computational biology has long held the promise of yielding practical insights for real-world application. AlphaFold has fulfilled this promise. Ahead of us lies a universe of new insights and scientific discoveries enabled by the use of AI as a scientific tool. I extend my gratitude to my colleagues over the years for making this moment of recognition possible, along with the many moments of discovery that lie ahead."

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